Combined treatment with modulated electro-hyperthermia and an autophagy inhibitor effectively inhibit ovarian and cervical cancer growth.

Wookyeom YangGwan Hee HanHa-Yeon ShinEun-Ju LeeHanbyoul ChoDoo Byung ChayJae-Hoon Kim

Published in: International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group (2018)

mEHT treatment alone was sufficient to inhibit cancer growth, while a combined treatment with mEHT and an autophagy inhibitor amplified this inhibition effect.

Keyphrases

cell death
oxidative stress
signaling pathway
endoplasmic reticulum stress