The tRNA-derived fragment 5026a inhibits the proliferation of gastric cancer cells by regulating the PTEN/PI3K/AKT signaling pathway.

Linwen ZhuZhe LiXiuchong YuYao RuanYijing ShenYongfu ShaoXinjun ZhangGuoliang YeJunming Guo

Published in: Stem cell research & therapy (2021)

tRF-5026a (tRF-18-79MP9P04) is a promising biomarker for gastric cancer diagnostics and has tumor suppressor effects mediated through the PTEN/PI3K/AKT signaling pathway.

Keyphrases

pi k akt
signaling pathway
cell cycle arrest
induced apoptosis
epithelial mesenchymal transition
cell proliferation
cell death
endoplasmic reticulum stress