Lipotoxicity-induced circGlis3 impairs beta cell function and is transmitted by exosomes to promote islet endothelial cell dysfunction.
Li XiongLi ChenLiting WuWeiman HeDubo ChenZishan PengJin LiXiaonan ZhuLei SuYanbing LiYingying GongHai-Peng XiaoPublished in: Diabetologia (2021)
The RNA-sequencing data have been deposited in the NCBI Sequence Read Archive (SRA) database, with accession number PRJNA689673. Mass spectrometry data are available via ProteomeXchange with identifier PXD024693.
Keyphrases
- mass spectrometry
- electronic health record
- high glucose
- endothelial cells
- big data
- mesenchymal stem cells
- single cell
- oxidative stress
- diabetic rats
- liquid chromatography
- single molecule
- emergency department
- drug induced
- data analysis
- adverse drug
- gas chromatography
- deep learning
- amino acid
- vascular endothelial growth factor