Clinical Outcomes and Management of NAAT-Positive/Toxin-Negative Clostridioides difficile Infection: A Systematic Review and Meta-Analysis.
Connor ProstyRyan HanulaKhaled KatergiYves LongtinEmily G McDonaldTodd C LeePublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2023)
Treatment of patients who were NAAT+/Toxin- was associated with reduced all-cause mortality, but not recurrence. While subject to the inherent limitations of observational studies, these results suggest that some patients who are NAAT+/Toxin- may benefit from treatment.