Sustained high fatality during TB therapy amid rapid decline in TB mortality at population level: A retrospective cohort and ecological analysis from Shiselweni, Eswatini.

Bernhard KerschbergerDebrah VambeMichael SchomakerEdwin MabhenaMichelle DakaThemba DlaminiSiphiwe NgwenyaBheki MambaBongekile NxumaloJoyce SibandaSisi DubeLindiwe Mdluli DlaminiEsther MukoozaTom EllmanIza Ciglenecki

Published in: Tropical medicine & international health : TM & IH (2023)

TB-related mortality rapidly decreased at population-level and most pronounced in PLHIV. However, case fatality among TB treatment cases remained high. Further strategies to reduce active TB disease and introduce improved TB therapies are warranted.

Keyphrases

mycobacterium tuberculosis
cardiovascular events
risk factors
type diabetes
climate change
replacement therapy