Efficacy of ketogenic diet in CDKL5-related epilepsy: a single arm meta-analysis.
Jie ZhangJiayi MaXuting ChangPengxia WuShangru LiYe WuPublished in: Orphanet journal of rare diseases (2022)
The definite responder rate to KD in CDKL5-related epilepsy was 18%, and the gastrointestinal adverse reactions were probably common in these patients. All the studies included in the meta-analysis were retrospective, and most of them had small sample sizes. Additional high-quality studies are needed to confirm the efficacy and tolerance of KD in CDKL5-related epilepsy.