The proangiogenic effects of extracellular vesicles secreted by dental pulp stem cells derived from periodontally compromised teeth.

Huan ZhouXuan LiYuan YinXiao-Tao HeYing AnBei-Min TianYong-Long HongLi-An WuFa-Ming Chen

Published in: Stem cell research & therapy (2020)

The findings of the present study provide additional evidence that P-DPSCs derived from periodontally diseased teeth represent a potential source of cells for research and therapeutic use. Particularly, the proangiogenic effects of P-EVs suggest that P-DPSCs may be used to promote new vessel formation in cellular therapy and regenerative medicine.

Keyphrases

stem cells
induced apoptosis
cell cycle arrest
cell therapy
oxidative stress
cell death
endoplasmic reticulum stress
risk assessment