A single-nucleotide polymorphism in the MicroRNA-146a gene is associated with diabetic nephropathy and sight-threatening diabetic retinopathy in Caucasian patients.

Georgia KaidonisMark C GilliesSotoodeh AbharyEbony LiuRohan W EssexJohn H ChangBishwanath PalSobha SivaprasadMaria PefkianakiMark DaniellStewart LakeNikolai PetrovskyAlex W HewittAlicia JenkinsEcosse L LamoureuxJonathan M GleadleJamie E CraigKathryn P Burdon

Published in: Acta diabetologica (2016)

Rs2910164 is significantly associated with microvascular complications DN in patients with T1DM and DME in patients with T2DM.

Keyphrases

diabetic retinopathy
diabetic nephropathy
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
optical coherence tomography
prognostic factors
peritoneal dialysis
genome wide
type diabetes
gene expression
skeletal muscle
dna methylation
patient reported outcomes
patient reported