Survival outcomes and toxicity profiles among patients with nonmetastatic nasopharyngeal carcinoma treated with intensity-modulated radiotherapy (IMRT) versus IMRT + carbon-ion radiotherapy: A propensity score-matched analysis.
Yujiao LiXiyin GuanXing XingChaosu HuPublished in: Head & neck (2024)
In this study, IMRT + CIRT was associated with significantly reduced acute toxicity burden compared with full course of IMRT, with excellent survival outcomes. Patients with persistent disease after treatment and treated with nodal boost had a worse outcome. More accurate assessments of IMRT + CIRT to primary nonmetastatic NPC patients will be imperative.
Keyphrases
- newly diagnosed
- early stage
- end stage renal disease
- oxidative stress
- ejection fraction
- locally advanced
- radiation therapy
- chronic kidney disease
- radiation induced
- liver failure
- prognostic factors
- neoadjuvant chemotherapy
- peritoneal dialysis
- squamous cell carcinoma
- high resolution
- lymph node
- drug induced
- intensive care unit
- acute respiratory distress syndrome