A novel nonlinear dimension reduction approach to infer population structure for low-coverage sequencing data.

Miao ZhangYiwen LiuHua ZhouJoseph WatkinsJin J Zhou

Published in: BMC bioinformatics (2021)

We apply MCPCA_PopGen to samples from two indigenous Siberian populations and reveal hidden population structure accurately using only a single chromosome. The MCPCA_PopGen package is available on https://github.com/yiwenstat/MCPCA_PopGen .

Keyphrases

single cell
electronic health record
genome wide
big data
copy number
affordable care act
genetic diversity
gene expression
healthcare
dna methylation
data analysis
machine learning
deep learning