Acid Enriched with Methanol: Formation of a Prebiotic Cluster in the Interstellar Medium.

Organic molecules are a potential source of prebiotic chemistry in the interstellar medium (ISM). Methanol (MetOH) is a very important source of more complex molecules. H 3 O + (aq) and Cl - (aq) are fundamental to living organisms and can be generated in the ISM from the dissociation of HCl with just four water molecules, yielding the (H 3 O) + (H 2 O) 3 Cl - ion-pair. Here, a detailed mechanism, based on density functional theory (DFT) and ab-initio (2 nd order Mϕller-Plesset perturbation theory, MP2) calculations, is suggested for the substitution reactions of these water molecules by MetOH. The time required for formation of an appreciable amount of the product ((H 3 O) + (MetOH) 3 Cl - ) can be only few years. Such reaction can take place in Sagittarius B2, where HCl, H 2 O and MetOH have already been identified and it can be an important source for the formation of more complex prebiotic structures.