Mutational profiles and prognostic impact in colorectal and high-grade appendiceal adenocarcinoma with peritoneal metastases.

Ryan B Morgan Ankit DhimanDivya SoodCecilia T OngXiaoyang WuArdaman ShergillBlase PoliteKiran Kalyan Turaga Oliver S Eng

Published in: Journal of surgical oncology (2023)

CRC and HGA with peritoneal spread have distinct mutational profiles. PIK3CA and TP53 mutations are associated with survival for CRC or HGA with peritoneal metastases, respectively.

Keyphrases

high grade
low grade
squamous cell carcinoma
radiation therapy
locally advanced