The acute effects of growth hormone in adipose tissue is associated with suppression of antilipolytic signals.
Katrine L HøyerMorten L HøgildEdward O ListKevin Y LeeEmily KissingerRita SharmaNils Erik MagnussonVishwajeet PuriJohn J KopchickJens Otto Lunde JørgensenNiels JessenPublished in: Physiological reports (2021)
(a) GH directly stimulates AT lipolysis in a GHR-dependent manner, (b) this involves suppression of antilipolytic signals at the level of gene expression, (c) the underlying GH signaling pathways remain to be defined.
Keyphrases
- growth hormone
- adipose tissue
- gene expression
- liver failure
- signaling pathway
- insulin resistance
- high fat diet
- dna methylation
- respiratory failure
- drug induced
- aortic dissection
- type diabetes
- epithelial mesenchymal transition
- metabolic syndrome
- hepatitis b virus
- pi k akt
- intensive care unit
- induced apoptosis
- oxidative stress