Ferroptosis is involved in corpus cavernosum smooth muscle cells impairment in diabetes mellitus-induced erectile dysfunction.

Wenchao Xu Taotao SunJiaxin WangTao WangShaogang WangJihong LiuKang LiuHao Li

Published in: Andrology (2022)

Our study revealed that ferroptosis may indeed exist in DMED. GPX4, SLC7A11, and ACSL4 all have a role in controlling the viability of CCSMCs, making them potential therapeutic targets.

Keyphrases

cell death
high glucose
skeletal muscle
metabolic syndrome
endothelial cells
adipose tissue
risk assessment