Ectopic Intrasphenoidal Growth Hormone Releasing Pituitary Adenoma Associated with an Intracranial Aneurysm.
Hernando Cifuentes-LobeloMarcelo A Castañeda-DuarteDiego Ruiz-DiazWilliam Cortes-LozanoPublished in: Asian journal of neurosurgery (2024)
Pituitary adenomas are a type of of the most frequent intracranial tumors. These tumors can extend outside the sella, but very rarely originate ectopically to the sellar region. A 71-year-old patient presented to our institution, with prior clinical history of noncontrolled arterial hypertension and new-onset high-intensity pulsatile headache. Upon suspicion of a hypertensive emergency with probable brain compromise, a nonenhanced computed tomography of the head was performed. A mass within the sphenoid sinus was found. Endocrinological workup demonstrated a significant elevation of the growth hormone. As an incidental finding, a brain aneurysm was evidenced, which was treated endovascularly prior to the mass treatment. Subsequently, the patient successfully underwent a gross total resection through an endonasal transsphenoidal approach. Histopathological results were consistent with a pituitary ectopic adenoma. A postoperative improvement in levels of somatomedin C was documented postoperatively.
Keyphrases
- growth hormone
- high intensity
- arterial hypertension
- computed tomography
- optic nerve
- coronary artery
- case report
- resting state
- white matter
- resistance training
- blood pressure
- emergency department
- public health
- healthcare
- patients undergoing
- functional connectivity
- positron emission tomography
- magnetic resonance imaging
- body composition
- blood brain barrier
- newly diagnosed
- replacement therapy
- children with cerebral palsy
- combination therapy
- subarachnoid hemorrhage
- emergency medical