Genetic variability in E6, E7 and L1 genes of Human Papillomavirus 62 and its prevalence in Mexico.

Cristina Artaza-IrigarayMaría Guadalupe Flores-MiramontesDominik OlszewskiMaría Teresa Magaña-TorresMaría Guadalupe López-CardonaYelda Aurora Leal-HerreraPatricia Piña-SánchezLuis Felipe Jave-SuárezAdriana Del Carmen Aguilar-Lemarroy

Published in: Infectious agents and cancer (2017)

HPV62 is a frequent HPV genotype found mainly in general population and in women with CIN1, and in 90.5% of the cases it was found in coinfection with other HPVs. Novel nucleotide changes in its L1, E6 and E7 genes were detected, some of them lead to changes in the protein sequence.

Keyphrases

genome wide
high grade
bioinformatics analysis
genome wide identification
dna methylation
risk factors
amino acid
copy number
cervical cancer screening
genome wide analysis
binding protein
gene expression
small molecule