Mass spectrometric analysis of 7-oxygenated androst-5-ene structures. Influence in trimethylsilyl derivative formation.
Dayamin Martinez-BritoXavier de la TorreMaria Kristina ParrFrancesco BotrePublished in: Rapid communications in mass spectrometry : RCM (2020)
The derivatization reagent, instrumental conditions (inlet), as well as the chemical structures of the analytes present in the matrix, can influence the results. So, before describing a new feature as a potential "new" metabolite, special caution must be taken since we could actually be dealing with an artifact.
Keyphrases
- high resolution
- machine learning
- ms ms
- liquid chromatography tandem mass spectrometry
- high performance liquid chromatography
- magnetic resonance imaging
- magnetic resonance
- simultaneous determination
- risk assessment
- computed tomography
- liquid chromatography
- human health
- mass spectrometry
- climate change
- solid phase extraction