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Rapid detection of carbapenemase-producing organisms directly from blood cultures positive for Gram-negative bacilli.

William StokesJohann PitoutLorraine CampbellDeirdre ChurchDaniel Gregson
Published in: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology (2020)
This study demonstrates that the detection of CPOs directly from positive BC can be accurately achieved. β CARBA had excellent sensitivity but suffered from poor specificity. CARBA 5 had good sensitivity and specificity but is unable to detect certain CPOs.
Keyphrases
  • gram negative
  • multidrug resistant
  • acinetobacter baumannii
  • klebsiella pneumoniae
  • structural basis
  • label free