Urinary podocyte-derived microparticles in youth with type 1 and type 2 diabetes.
Katie M SullivanJames ScholeyRahim MoineddinEtienne SochettBrandy WicklowYesmino EliaFeng XiaoThalia MederiosPusha SadiDylan BurgerFarid H MahmudAllison B DartPublished in: Diabetologia (2020)
Significant associations between podocyte MPE, blood glucose levels and eGFR were observed in youth with type 1 diabetes but not in those with type 2 diabetes, notwithstanding increased renal pathology in the type 2 diabetes cohort. These findings suggest that podocyte injury differs in the two diabetes cohorts. Graphical abstract.