The HMGA1-pseudogene7 shows oncogenic activity in vivo.
Marco De MartinoFrancesco EspositoAlfredo FuscoPublished in: Cell cycle (Georgetown, Tex.) (2020)
We have recently reported that transgenic mice overexpressing the HMGA1-pseudogene7 develop hematological neoplasia marked by monoclonal B-cell populations, and diagnosed as Diffuse Large B-cell Lymphoma. These findings prove the HMGA1-pseudogene7 oncogenic role in vivo.