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Mendelian gene identification through mouse embryo viability screening.

Pilar CacheiroCarl Henrik WesterbergJesse MagerMary E DickinsonLauryl M J NutterVioleta Muñoz-FuentesChih-Wei HsuIgnatia B Van den VeyverAnn M FlennikenColin McKerlieStephen A MurrayLydia TeboulJason D HeaneyK C Kent LloydLouise LanoueRobert E BraunJacqueline K WhiteAmie K CreightonValerie LaurinRuolin GuoDawei QuSara WellsJames CleakRosie Bunton-StasyshynMichelle StewartJackie HarrissonJeremy MasonHamed Haseli MashhadiHelen ParkinsonAnn-Marie Mallonnull nullnull nullDamian Smedley
Published in: Genome medicine (2022)
Information on the developmental period at which embryonic lethality occurs in the knockout mouse may be used for novel disease gene discovery that helps to prioritise variants in unsolved rare disease cases.
Keyphrases
  • copy number
  • genome wide
  • small molecule
  • genome wide identification
  • high throughput
  • healthcare
  • dna methylation
  • health information
  • pregnant women