Serum levels of interleukin-22, cardiometabolic risk factors and incident type 2 diabetes: KORA F4/FF4 study.

Christian HerderJulia M KannenbergMaren Carstensen-KirbergCornelia HuthChrista MeisingerWolfgang KoenigAnnette PetersWolfgang RathmannMichael RodenBarbara Thorand

Published in: Cardiovascular diabetology (2017)

High serum levels of IL-22 were positively rather than inversely associated with several cardiometabolic risk factors. However, these associations did not translate into an increased risk for type 2 diabetes. Thus, our data argue against the utility of IL-22 as biomarker for prevalent or incident type 2 diabetes in humans, but identify potential determinants of IL-22 levels which merits further research in the context of cardiovascular diseases.

Keyphrases

type diabetes
cardiovascular disease
risk factors
glycemic control
insulin resistance
cardiovascular risk factors
electronic health record
machine learning
metabolic syndrome
risk assessment
climate change
cardiovascular events
weight loss
data analysis
deep learning