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Clinicopathologic features of breast cancers diagnosed in women treated with prior radiation therapy for Hodgkin lymphoma: Results from a population-based cohort.

Stephanie M WongLissa AjjamadaAnna C WeissIpshita PrakashSonia SkameneJean Francois BoileauMichael N PollakMark Basik
Published in: Cancer (2021)
Women who have had radiation therapy for Hodgkin lymphoma at a young age are at increased risk of developing early onset breast cancer; however, most of these breast cancers are sensitive to hormones (estrogen receptor-positive) and are diagnosed at early stages. Because these breast tumors are estrogen receptor-positive, medications that prevent breast cancer by blocking the effect of or lowering hormone levels (also termed endocrine prevention) may be useful in this group of high-risk women.
Keyphrases
  • estrogen receptor
  • hodgkin lymphoma
  • early onset
  • polycystic ovary syndrome
  • breast cancer risk
  • pregnancy outcomes
  • late onset
  • pregnant women
  • insulin resistance
  • skeletal muscle
  • adipose tissue
  • newly diagnosed