Circulating levels of cell adhesion molecules and risk of cardiovascular events in obstructive sleep apnea.
Bernardo U PeresA J Hirsch AllenPatrick DanieleKarin H HumphriesCarolyn TaylorIsmail LaherFernanda R AlmeidaRachel JenAndrew J SandfordStephan F van EedenNajib T AyasPublished in: PloS one (2021)
In a suspected OSA cohort, patients with higher levels of ICAM-1 (>816 ng/ml) were significantly more likely to experience a cardiovascular event within 8 years after PSG. In moderate to severe OSA patients, a higher E-selectin (>36.4 ng/ml) was significantly associated with cardiovascular events.
Keyphrases
- cardiovascular events
- obstructive sleep apnea
- coronary artery disease
- cardiovascular disease
- cell adhesion
- positive airway pressure
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- peritoneal dialysis
- prognostic factors
- high intensity
- sleep apnea
- patient reported outcomes
- patient reported