Systemic vascular basement membrane markers linked to synovial vascular remodeling are biomarkers of hemarthrosis in patients with hemophilia.
Srila GopalRichard F W BarnesEsther J CookeJenny Y ZhouIlana LevinPamela EmeryTudor H HughesMorten A KarsdalTina Manon-JensenAnnette von DrygalskiPublished in: Journal of thrombosis and haemostasis : JTH (2021)
Our findings suggest that basement membrane turnover markers, closely linked to synovial vascular remodeling, may be systemic biomarkers of acute hemarthrosis. Vascular instability during neovascularization may be involved in the dynamics of hemarthrosis.