Prognostic value of isolated tumor cells in sentinel lymph nodes in low risk endometrial cancer: results from an international multi-institutional study.
Giuseppe CucinellaGabriella SchivardiXun Clare ZhouMariam AlHilliSumer WallaceChristoph WohlmuthGlauco BaiocchiNedim TokgozogluFrancesco RaspagliesiAlessandro BudaVanna ZanagnoloIgnacio Zapardiel GutiérrezNisha JagasiaRobert GiuntoliAriel GlickmanMichele PeirettiMaximilian LannerEnrique ChacónJulian Di GuilmiAugusto PereiraEnora Laas-FaronAmi FishmanCaroline C NitschmannKatherine C KurnitKristen MoriartyAmy Joehlin-PriceBrittany LeesAllan CovensLouise De BrotCagatay TaskıranGiorgio BoganiFabio LandoniTommaso GrassiCristiana PanigaFrancesco MultinuLuigi Antonio De VitisAlicia HernándezSpyridon MastroyannisKhaled GhoniemVito ChianteraMaryam ShahiAngela J FoughtMichaela McGreeAndrea MarianiGretchen E GlaserPublished in: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society (2023)
Patients with SLNs-isolated tumor cells and low risk profile, without adjuvant therapy, had a significantly worse recurrence free survival compared with node negative patients with similar risk factors, after adjusting for grade and excluding patients with lymphovascular space invasion. However, the presence of SLNs-isolated tumor cells was not associated with worse overall survival.