Increased risk of severe neonatal opioid withdrawal syndrome in pregnancies with low placental ABCB1 DNA methylation.

Courtney TownselBurnley TruaxMargaret QuaidJonathan CovaultDana C DolinoyJaclyn M Goodrich

Published in: Journal of perinatology : official journal of the California Perinatal Association (2024)

Lower placental ABCB1 methylation was associated with severe NOWS. Higher placental CYP19A1 methylation correlated with higher umbilical cord norbuprenorphine levels.

Keyphrases

dna methylation
umbilical cord
genome wide

mesenchymal stem cells
early onset
gene expression

chronic pain
copy number
gestational age

bone marrow
pregnant women