Weekly cisplatin chemotherapy dosing versus triweekly chemotherapy with concurrent radiation for head and neck squamous cell carcinoma.

Ryan T MorseRohit G GanjuMindi J TenNapelPrakash NeupaneKiran KakaralaYelizaveta ShnayderAllen M Chen Christopher E Lominska

Published in: Head & neck (2019)

Our study displayed inferior outcomes with weekly cisplatin doses under 40 mg/m2 , suggesting the inferiority of low-dose weekly chemotherapy and the need for ongoing randomized trials to further explore 40 vs 100 mg/m2 chemotherapy regimens.

Keyphrases

locally advanced
low dose
rectal cancer
squamous cell carcinoma
radiation therapy
high dose
chemotherapy induced
metabolic syndrome