Distribution of insulin in primate brain following nose-to-brain transport.

Kylie R SmithJinda FanGwendolyn A MarrinerJohn GerdesRobert KesslerKurt R Zinn

Published in: Alzheimer's & dementia (New York, N. Y.) (2024)

F]FB-insulin activity was highest in emotional and memory processing regions.Aerosol delivery was less efficient than liquid instillation by preplaced catheter.Insulin delivery to the cribriform plate was critical for arrival in the brain.

Keyphrases

type diabetes
resting state
white matter
glycemic control
functional connectivity
cerebral ischemia
working memory
multiple sclerosis
metabolic syndrome
brain injury
ionic liquid
adipose tissue
weight loss
blood brain barrier
insulin resistance
subarachnoid hemorrhage