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A simple, rapid and low-cost qPCR assay for evaluating the severity of exosomal PD-L1-mediated T cell exhaustion in blood samples.

Renhui ZhanShanshan WangWenfei GuoXiaonan GaoXiaojun LiuKehua XuBo Tang
Published in: Chemical communications (Cambridge, England) (2022)
A novel dual-aptamer activated proximity-induced qPCR assay was developed for the quantitative analysis of exosomal PD-L1 on T cell-exosome complexes in blood samples.
Keyphrases
  • low cost
  • high throughput
  • gold nanoparticles
  • diabetic rats
  • sensitive detection
  • drug induced
  • single cell