Remote Ischemic Perconditioning Ameliorates Myocardial Ischemia and Reperfusion-Induced Coronary Endothelial Dysfunction and Aortic Stiffness in Rats.
Petra Lujza SzabóChristopher DostalPatrick Michael PilzOuafa HamzaEylem AcarSimon WatzingerShalett MathewGerd KagerSeth HallströmBruno Karl PodesserAttila KissPublished in: Journal of cardiovascular pharmacology and therapeutics (2021)
Our study for the first time demonstrated that RIPerc alleviates MIR-induced coronary artery endothelial dysfunction in non-occluded artery segments and attenuates aortic stiffness in rats. The vascular protective effects of RIPerc are associated with ameliorated inflammation and might therefore be caused by reduced inflammatory signaling.
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