Distinguishing SARS-CoV-2 persistence and reinfection: A retrospective cohort study.
Sarah E TurbettChristopher H Tomkins-TinchMelis N AnahtarCaitlin M DugdaleEmily P HyleErica S ShenoyBennett ShawKenechukwu EgbuonuKathryn A BowmanKimon C ZacharyGordon C AdamsDavid C HooperEdward T RyanRegina C LaRocqueIngrid V BassettVirginia A TriantKatherine J SiddleEric RosenbergPardis C SabetiStephen F SchaffnerBronwyn L MacInnisJacob E LemieuxRichelle C CharlesPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2022)
Despite good overall concordance with viral genomic analysis, clinical and Ct value-based assessments failed to identify 33% of genomically-supported reinfections. Scaling-up genomic analysis for clinical use would improve detection of SARS-CoV-2 reinfections.