The Relationship Between Single Nucleotide Polymorphisms of SMAD3/SMAD6 and Risk of Esophageal Squamous Cell Carcinoma in Chinese Population.
Jinjie YuYunpeng DongWeifeng TangHuiwen PanLu LvTao LongQiang ZhouJunqing QiJianchao LiuGuowen DingJun YinLijie TanPublished in: Pharmacogenomics and personalized medicine (2020)
SNPs of SMAD3 were related to higher susceptibility to ESCC. As such, they may contribute to the development of viable strategies for early diagnosis and treatment of ESCC. However, more detailed association mechanisms between SMAD3/SMAD6 SNPs and ESCC need further experiments to prove.