High Rates of Seroprotection and Seroconversion to Vaccine-Preventable Infections in the Early Post-Autologous Stem Cell Transplant Period.

Victoria G HallNatalie R SaundersEmily KlimevskiGayani S TennakoonAmit KhotSimon HarrisonLeon J WorthMichelle K YongMonica A SlavinBenjamin W Teh

Published in: Open forum infectious diseases (2023)

In patients early post-autologous stem cell transplant, seroprotection rates were high for Hemophilus influenzae type B and tetanus toxoid (70%-90%) but lower for Streptococcus pneumoniae (30%-50%) including after revaccination. There were high rates of seropositivity (67%-86%) to measles, mumps, and rubella and varicella zoster virus. Durability of protection requires assessment.

Keyphrases

stem cells
end stage renal disease
cell therapy
bone marrow
ejection fraction
chronic kidney disease
newly diagnosed
peritoneal dialysis
emergency department
prognostic factors