Validation of a genetic-enhanced risk prediction model for colorectal cancer in a large community-based cohort.
Yu-Ru SuLori C SakodaJihyoun JeonMinta ThomasYi LinJennifer S HaasNatalia UdaltsovaJeffrey K LeeIris Lansdorp-VogelaarElisabeth F P PeterseAnn G ZauberJiayin ZhengYingye ZhengElizabeth R HauserJohn A BaronElizabeth L BarryD Timothy BishopHermann BrennerDaniel D BuchananAndrea N Burnett-HartmanPeter T CampbellGraham CaseySergi Castellví-BelAndrew T ChanJenny Chang-ClaudeJane C FigueiredoSteven J GallingerGraham G GilesStephen B GruberAndrea GsurMarc J GunterJochen HampeHeather HampelTabitha A HarrisonMichael HoffmeisterXinwei HuaJeroen R HuygheMark E JenkinsTemitope O KekuLoic Le MarchandLi LiAnnika LindblomVictor MorenoPolly A NewcombPaul D P PharoahElizabeth A PlatzJohn D PotterConghui QuGadi RennertRobert E SchoenMartha L SlatteryMingyang SongFranzel J B van DuijnhovenBethany Van GuelpenPavel VodickaAlicja WolkMichael O WoodsAnna H WuRichard B HayesUlrike PetersDouglas A CorleyLi HsuPublished in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2023)
The proposed model has potential utility in risk-stratified CRC prevention.