CSF Concentrations of CXCL13 and sCD27 Before and After Autologous Hematopoietic Stem Cell Transplantation for Multiple Sclerosis.

Katarina LundbladChristina ZjukovskajaAnders LarssonHonar CherifKim KultimaJoachim Burman

Published in: Neurology(R) neuroimmunology & neuroinflammation (2023)

After AHSCT for RRMS, CSF concentrations of CXCL13 were rapidly normalized, whereas sCD27 decreased gradually over the course of 2 years. Thereafter, the concentrations remained stable throughout follow-up, indicating that AHSCT induced long-lasting biological changes.

Keyphrases

multiple sclerosis
acute myeloid leukemia
bone marrow
high glucose
white matter
endothelial cells
mesenchymal stem cells