Beta arrestin-related signalling axes are influenced by dexamethasone and metformin in vascular smooth muscle cells cultured in high glucose condition.

Ali Akbar SoleimaniNafiseh ShokriMohammad ElahimaneshPayam MohammadiNajmeh ParvazMasoomeh BakhshandehMohammad Najafi

Published in: Endocrinology, diabetes & metabolism (2023)

Met and Dexa suppressed the BARR2 protein and gene expression levels in the VSMCs. Moreover, the gene network suggested some the cellular signalling axes related to BARR2 that may be affected by Met and Dexa.

Keyphrases

vascular smooth muscle cells
high glucose
gene expression
endothelial cells
angiotensin ii
tyrosine kinase
dna methylation
low dose
genome wide
copy number
protein protein