Quantitative PET imaging of the CD4 pool in nonhuman primates.

Insook KimSharat SrinivasulaPaula DeGrangeBrad LongHyukjin JangJorge A CarrasquilloH Clifford LaneMichele Di Mascio

Published in: European journal of nuclear medicine and molecular imaging (2022)

The majority of specific binding to CD4 + tissue was localized to LNs and spleen with minimal uptake in the gut. Binding potential derived from fully quantitative studies revealed that the contribution of the gut is lower than the spleen's contribution to the total body CD4 pool.

Keyphrases

pet imaging
nk cells
single cell
computed tomography
mass spectrometry