Apoptotic collopathy as a manifestation of Good's syndrome.
Margarita ReyDaniela RicoRocío Del Pilar López PanquevaMariana Vásquez-RoldanPublished in: Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva (2021)
44-year-old patient with 4 years of evolution of recurrent respiratory infections, fever, weight loss of 30 kg and chronic diarrhea with inconclusive colonoscopy studies managed as IBD (inflammatory bowel disease). A colonoscopy was performed with an infectious aspect vs IBD, the biopsies revealed acute colitis with cryptic apoptosis without evidence of chronicity. So is considered another type of immunodeficiency with the presence of hypogammaglobulinemia, reaching the diagnosis of Good's syndrome due to the association with thymoma and recurrent infections.
Keyphrases
- case report
- weight loss
- ulcerative colitis
- cell death
- liver failure
- bariatric surgery
- oxidative stress
- endoplasmic reticulum stress
- cell cycle arrest
- respiratory failure
- roux en y gastric bypass
- cell proliferation
- adipose tissue
- gastric bypass
- signaling pathway
- irritable bowel syndrome
- respiratory tract
- hepatitis b virus
- mechanical ventilation
- obese patients