Prognostic significance of estrogen, progesterone and HER2 receptors' status conversion following neoadjuvant chemotherapy in patients with locally advanced breast cancer: Results from a tertiary Cancer Center in Saudi Arabia.
Khalid Al-SalehTareq SalahMaria A ArafahSufia HusainAmmar Al-RikabiNashwa M Abdel AzizPublished in: PloS one (2021)
Patients with LABC have significant changes in the ER and PR receptor status following NAC. Post-NAC expressions change of ER and PR (ER and/or PR) are correlated to DFS. Retesting of the hormone receptors should be considered after NAC in Saudi patients with LABC.
Keyphrases
- neoadjuvant chemotherapy
- estrogen receptor
- locally advanced
- transcription factor
- rectal cancer
- endoplasmic reticulum
- lymph node
- squamous cell carcinoma
- sentinel lymph node
- breast cancer cells
- radiation therapy
- phase ii study
- genome wide analysis
- papillary thyroid
- squamous cell
- saudi arabia
- clinical trial
- open label
- childhood cancer
- lymph node metastasis
- binding protein
- breast cancer risk