Heat shock protein 70 potentiates interferon alpha production by plasmacytoid dendritic cells: relevance for cutaneous lupus and vitiligo pathogenesis.

C JacqueminJ RambertS GuilletD ThiolatN BoukhedouniM-S DoutreAnne-Sophie DarrigadeK EzzedineP BlancoA TaiebK BonifaceJ Seneschal

Published in: The British journal of dermatology (2017)

These data demonstrate that interaction between HSP70 and pDCs in CLE and vitiligo is a prerequisite for the enhancement of IFN-α production, and could be an interesting target.

Keyphrases

dendritic cells
heat shock protein
heat shock
regulatory t cells
immune response
systemic lupus erythematosus
electronic health record
disease activity
big data
machine learning