6-Dihydroparadol, a Ginger Constituent, Enhances Cholesterol Efflux from THP-1-Derived Macrophages.

Dongdong WangVerena HieblAngela LadurnerSimone L LatkolikFranz BucarElke H HeißVerena M DirschAtanas Georgiev Atanasov

Published in: Molecular nutrition & food research (2018)

We identified 6-dihydroparadol from ginger as a novel promoter of cholesterol efflux from macrophages that increases both ABCA1 and ABCG1 protein abundance. This newly identified bioactivity might contribute to the antiatherogenic effects of ginger.

Keyphrases

low density lipoprotein
dna methylation
gene expression
transcription factor
protein protein
antibiotic resistance genes