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6-Dihydroparadol, a Ginger Constituent, Enhances Cholesterol Efflux from THP-1-Derived Macrophages.

Dongdong WangVerena HieblAngela LadurnerSimone L LatkolikFranz BucarElke H HeißVerena M DirschAtanas Georgiev Atanasov
Published in: Molecular nutrition & food research (2018)
We identified 6-dihydroparadol from ginger as a novel promoter of cholesterol efflux from macrophages that increases both ABCA1 and ABCG1 protein abundance. This newly identified bioactivity might contribute to the antiatherogenic effects of ginger.
Keyphrases
  • low density lipoprotein
  • dna methylation
  • gene expression
  • transcription factor
  • protein protein
  • antibiotic resistance genes