Bioresorbable Magnesium-Based Stent: Real-World Clinical Experience and Feasibility of Follow-Up by Coronary Computed Tomography: A New Window to Look at New Scaffolds.
Chadi GhafariNicolas BrassartPhilippe DelmottePhilippe BrunnerSarah DghoughiStephane CarlierPublished in: Biomedicines (2023)
(1) Background: The diagnostic accuracy of coronary computed tomography angiography (CCTA) for coronary artery disease (CAD) has greatly improved so CCTA represents a transition in the care of patients suffering from CAD. Magnesium-based bioresorbable stents (Mg-BRS) secure acute percutaneous coronary intervention (PCI) results without leaving, in the long term, a metallic caging effect. The purpose of this real-world study was to assess clinical and CCTA medium- and long-term follow-up of all our patients with implanted Mg-BRS. (2) Methods: The patency of 52 Mg-BRS implanted in 44 patients with de novo lesions (24 of which had acute coronary syndrome (ACS)) was evaluated by CCTA and compared to quantitative coronary angiography (QCA) post-implantation. (3) Results: ten events including four deaths occurred during a median follow-up of 48 months. CCTA was interpretable and in-stent measurements were successful at follow-up without being hindered by the stent strut's "blooming effect". Minimal in-stent diameters on CCTA were found to be 1.03 ± 0.60 mm smaller than the expected diameter after post-dilation on implantation ( p < 0.05), a difference not found in comparing CCTA and QCA. (4) Conclusions: CCTA follow-up of implanted Mg-BRS is fully interpretable and we confirm the long-term Mg-BRS safety profile.
Keyphrases
- coronary artery disease
- percutaneous coronary intervention
- acute coronary syndrome
- coronary artery bypass grafting
- cardiovascular events
- computed tomography
- antiplatelet therapy
- st segment elevation myocardial infarction
- st elevation myocardial infarction
- acute myocardial infarction
- coronary artery
- healthcare
- end stage renal disease
- ejection fraction
- magnetic resonance imaging
- type diabetes
- newly diagnosed
- palliative care
- quality improvement
- chronic kidney disease
- prognostic factors
- liver failure
- magnetic resonance
- atrial fibrillation
- pain management
- transcatheter aortic valve replacement
- image quality
- aortic dissection
- respiratory failure