Metabolic Correlates of Dopaminergic Loss in Dementia with Lewy Bodies.
Maria HuberLeonie BeyerCatharina PrixSonja SchöneckerCarla PalleisBoris-Stephan RauchmannSilvia MorbelliAndrea ChincariniRose BruffaertsRik VandenbergheKoen Van LaereMilica G KrambergerMaja TrostMarko GrmekValentina GaribottoNicolas NicastroGiovanni B FrisoniAfina W LemstraJessica van der ZandeAndrea PilottoAlessandro PadovaniSara Garcia-PtacekIrina SavitchevaMiguel A Ochoa-FigueroaAnette DavidssonValle CamachoEnrico PeiraDario ArnaldiMatteo BaucknehtMatteo PardiniGianmario SambucetiJonathan VögleinJonas SchnabelMarcus UnterrainerRobert PerneczkyOliver PogarellKatharina BuergerCihan CatakPeter BartensteinPaul CummingMichael EwersAdrian DanekJohannes LevinDag AarslandFlavio NobiliAxel RomingerMatthias BrendelPublished in: Movement disorders : official journal of the Movement Disorder Society (2019)
Relative glucose hypermetabolism and disturbed metabolic connectivity of limbic and basal ganglia circuits are metabolic correlates of dopamine deficiency in dementia with Lewy bodies. Identification of specific metabolic network alterations in patients with early dopamine deficiency may serve as an additional supporting biomarker for timely diagnosis of dementia with Lewy bodies. © 2019 The Authors. Movement Disorders published by Wiley Periodicals, Inc. on behalf of International Parkinson and Movement Disorder Society.