Holmium complex with phospholipids as 1 H NMR temperature probe for membrane systems.

Olga Yu SelyutinaV E KoshmanM V ZelikmanS P Babailov

Published in: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine (2022)

The temperature dependence of the lanthanide-induced chemical shifts (LISs) was studied for the systems containing 1-palmitoyl-2-oleoylphosphatidylcholine (POPC)-Ho, 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC)-Ho and 1,2-dimyristoyl-sn-glycero-3-phosphorylcholine (DMPC)-Ho in unilamellar liposomes. In the POPC-Ho system, anti-Curie dependence of LISs is observed, same as previously observed in POPC-Pr system. In the DPPC- and DMPC-Ho systems, temperature features are observed which are probably connected with phase transition.

Keyphrases

pi k akt
magnetic resonance
drug delivery
high resolution
high glucose
cell proliferation
mass spectrometry
drug release
oxidative stress
living cells