Subthalamic Nucleus Deep Brain Stimulation Modulates 2 Distinct Neurocircuits.

Lunhao ShenChangqing JiangCatherine S HubbardJianxun RenChanggeng HeDanhong WangLouisa DahmaniYi GuoYiming LiuShujun XuFangang MengJianguo ZhangHesheng LiuLuming Li

Published in: Annals of neurology (2020)

Concurrent DBS-fMRI using 3T revealed 2 distinct circuits that responded differentially to STN-DBS and were related to divergent symptoms, a finding that may provide novel insights into the neural mechanisms underlying DBS. ANN NEUROL 2020;88:1178-1193.

Keyphrases

deep brain stimulation
parkinson disease
obsessive compulsive disorder
resting state
functional connectivity
single cell
locally advanced
squamous cell carcinoma
neural network
physical activity
drug induced