BLK and BANK1 polymorphisms and interactions are associated in Mexican patients with systemic lupus erythematosus.

Julián Ramírez BelloSilvia Jiménez-MoralesIsela Montufar-RoblesJosé M FragosoRosa Elda Barbosa-CobosMiguel A SaavedraFausto Sánchez-Muñoz

Published in: Inflammation research : official journal of the European Histamine Research Society ... [et al.] (2019)

This is the first study documenting an association between BLK and BANK1 and SLE in a Latin-American population. Our data confirm previous reports: BLK and BANK1 are factors associated with SLE. Thus, both genes are universal loci for this autoimmune disease.

Keyphrases

rheumatoid arthritis
disease activity
systemic lupus erythematosus
genome wide
multiple sclerosis
dna methylation
gene expression
transcription factor
genome wide association