An Adaptive Information Borrowing Platform Design for Testing Drug Candidates of COVID-19.

Liwen Su Jingyi Zhang Fangrong Yan

Published in: The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale (2022)

Our proposed design achieves the goal of gaining efficiency, saving sample size, meeting ethical requirements, and speeding up the trial process and is suitable and well performed for COVID-19 clinical trials to screen promising treatments or target optimal therapies.

Keyphrases

coronavirus disease
clinical trial
sars cov
high throughput
phase ii
phase iii
study protocol
respiratory syndrome coronavirus
open label
health information
healthcare
emergency department
social media
single cell