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Veterans Affairs Pharmacogenomic Testing for Veterans (PHASER) clinical program.

Olivia M DongJill BatesCatherine Chanfreau-CoffinierMichael NaglichMichael J KelleyLaurence J MeyerMichael IcardiJason L VassyPeruvemba SriramCraig William HeiseSalvador RivasMaria RibeiroRussell JacobitzSusan RozelleJennifer G ChapmanDeepak Voora
Published in: Pharmacogenomics (2021)
In 2019, the Veterans Affairs (VA), the largest integrated US healthcare system, started the Pharmacogenomic Testing for Veterans (PHASER) clinical program that provides multi-gene pharmacogenomic (PGx) testing for up to 250,000 veterans at approximately 50 sites. PHASER is staggering program initiation at sites over a 5-year period from 2019 to 2023, as opposed to simultaneous initiation at all sites, to facilitate iterative program quality improvements through Plan-Do-Study-Act cycles. Current resources in the PGx field have not focused on multisite, remote implementation of panel-based PGx testing. In addition to bringing large scale PGx testing to veterans, the PHASER program is developing a roadmap to maximize uptake and optimize the use of PGx to improve drug response outcomes.
Keyphrases
  • quality improvement
  • primary care
  • type diabetes
  • metabolic syndrome
  • magnetic resonance imaging
  • computed tomography
  • copy number
  • transcription factor
  • weight loss
  • insulin resistance
  • skeletal muscle
  • glycemic control