Serum neurofilament light chain in pediatric MS and other acquired demyelinating syndromes.
Yu Yi M WongArlette L BruijstensChristian BarroZuzanna MichalakMarie-José MeliefAnnet F WierengaE Daniëlle van PeltRinze Frederik NeuteboomJens KuhleRogier Q HintzenPublished in: Neurology (2019)
The significant correlation between CSF and serum NfL strengthens its reliability as a peripheral marker of neuroaxonal damage. Higher sNfL levels at baseline were associated with higher probability of future CDMS diagnosis in ADS-.